Plasmapheresis can correct refractoriness of insulin on triglyceride metabolism – A case report of hypertriglyceridemia-induced acute pancreatitis

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Published May 18, 2023
DOI: https://doi.org/10.22551/2023.39.1002.10244
Bala Sundaram http://orcid.org/0000-0003-2392-9640 Nabadwip Pathak http://orcid.org/0000-0002-7089-0446 Sunil Kumar Nanda http://orcid.org/0000-0002-2125-0776

Abstract

Hypertriglyceridemia associated acute pancreatitis is a medical emergency and it causes significant morbidity and mortality. Here we report a case of 47 years old male with hypertriglyceridemia associated acute pancreatitis. The diagnosis was confirmed by elevated serum triglyceride levels and elevated lipase levels. Initially, Insulin infusion started with fibrates and statins but due to worsening hypertriglyceridemia and he underwent one session of plasmapheresis, following which triglyceride levels improved. Triglyceride assessment in removed plasma in plasmapheresis showed that the amount of triglyceride level reduction was 4 times the amount removed in plasmapheresis. The study showed that plasmapheresis improves insulin-related triglyceride metabolism besides removal.

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Keywords

Plasmapheresis, Insulin, Hypertriglycerdemia, Acute pancreatitis

References
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How to Cite
Sundaram, B., Pathak, N., & Nanda, S. K. (2023). Plasmapheresis can correct refractoriness of insulin on triglyceride metabolism – A case report of hypertriglyceridemia-induced acute pancreatitis. Archive of Clinical Cases, 10(2), Arch Clin Cases. 2023;10(2):70-73. https://doi.org/10.22551/2023.39.1002.10244
Issue
Vol. 10 No. 2 (2023)
Section
Case Reports

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How to Cite

Sundaram, B., Pathak, N., & Nanda, S. K. (2023). Plasmapheresis can correct refractoriness of insulin on triglyceride metabolism – A case report of hypertriglyceridemia-induced acute pancreatitis. Archive of Clinical Cases, 10(2), Arch Clin Cases. 2023;10(2):70-73. https://doi.org/10.22551/2023.39.1002.10244