Hypofibrinogenemia and miscarriage: report of a first successful pregnancy under fibrinogen substitution and short review of the literature

Christoph Sucker, Christof Geisen, Ursula Schmitt, Bartosz Zawislak


Disorders of fibrinogen have been reported to be associated not only with bleeding and thrombosis but also with miscarriage. Here, we report the case of a woman with genetically determined hypofibrinogenemia and recurrent miscarriages who had a first successful pregnancy under fibrinogen substitution. Current knowledge on fibrinogen disorders and recurrent miscarriages is briefly summarized and discussed.


miscarriage; hypofibrinogenemia; fibrinogen substitution

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DOI: http://dx.doi.org/10.22551/2022.36.0903.10211

Copyright (c) 2022 Christoph Sucker, Christof Geisen, Ursula Schmitt, Bartosz Zawislak

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ISSN: 2360-6975