Secondary thyroid malignancy – a rare clinical finding?

Marius-Lucian Mitrache, Gheorghiță Patriciu Zubașcu, Teodor Dumitraș, Carmen Sorina Martin, Simona Fica

Abstract


Metastases to the thyroid gland, while rarely seen in clinical practice, can pose a diagnostic and therapeutic challenge. Most commonly, they originate from lung, renal, and breast cancer, and are generally a sign of multiorgan metastatic disease. In most cases, metastases to the thyroid gland are diagnosed incidentally on imaging studies, since they are rarely symptomatic and often do not influence thyroid function tests. Thyroid ultrasonography and fine-needle aspiration biopsy play a pivotal role in their evaluation, as both classic immunocytochemical features, and more novel molecular markers can help in the differential diagnosis. Prognosis mainly depends on the biology of the primary tumor and its extension. Communication between clinicians is essential in such patients, in order to ensure that the treatment options are carefully balanced, thus raising the need for multidisciplinary teams in their management.

Keywords


metastasis to the thyroid; secondary malignancy

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References


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DOI: http://dx.doi.org/10.22551/2021.33.0804.10192

Copyright (c) 2021 Marius-Lucian Mitrache, Gheorghiță Patriciu Zubașcu, Teodor Dumitraș, Carmen Sorina Martin, Simona Fica

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