Rasaki Aliu http://orcid/org/0000-0002-2961-6891 Lawan Ibrahim Aliyu Patience Ngozi Obiagwu Lukman Olatoke Joseph Kelechi Ebisike

Abstract

Juvenile Dermatomyositis is a rare idiopathic autoimmune and inflammatory myopathy and vasculopathy whose hallmarks are symmetrical proximal muscle weaknesses and a characteristic rash. Only few cases have been reported in West Africa subregion. We present a 14-year old Nigerian girl with clinical and histopathologic features of definitive juvenile dermatomyositis based on EULAR/ACR classification criteria but probable Juvenile dermatomyositis according to Bohan and Peter criteria. The patient had normal aspartate and alanine aminotransferase levels. Creatine kinase, Lactate dehydrogenase and aldolase which are not available in our center could not be evaluated. There was remarkable clinical improvement 3 weeks after the onset of systemic corticosteroid therapy. Our case highlights that relying on these normal enzyme values, especially where muscle biopsy and EMG are not available as is the case in most centers in developing countries, would have resulted in missed diagnosis using Bohan and Peter criteria.

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Keywords

juvenile dermatomyositis, autoimmune vasculopathy, muscle biopsy

References
1. Oddis C, Conte C, Steen V, Medsger TA Jr. Incidence of polymyositis-dermatomyositis: a 20-year study of hospital diagnosed cases in Allegheny County, PA 1963-1982. J Rheumatol 1990; 17(10):1329-1334.
2. Symmons DP, Sills JA, Davis SM. The incidence of juvenile dermatomyositis: results from a nation-wide study. Br J Rheumatol 1995; 34(8):732-736.
3. Mendez EP, Lipton R, Ramsey‐Goldman R, et al. US incidence of juvenile dermatomyositis, 1995–1998: results from the National Institute of Arthritis and Musculoskeletal and Skin Diseases Registry. Arthritis Rheum 2003; 49(3):300-305.
4. Ramanan AV, Feldman BM. Clinical features and outcomes of juvenile dermatomyositis and other childhood onset myositis syndromes. Rheum Dis Clin North Am 2002; 28(4):833-857.
5. Bohan A, Peter JB. Polymyositis and dermatomyositis (second of two parts). N Engl J Med 1975; 292(8):403-407.
6. Lundberg IE, Tjärnlund A, Bottai M, et al. 2017 European League Against Rheumatism/ American College of Rheumatology classification criteria for adult and juvenile idiopathic inflammatory myopathies and their major subgroups. Arthritis Rheumatol 2017; 69(12):2271-2282.
7. Martin N, Krol P, Smith S, et al. Juvenile Dermatomyositis Research Group. A national registry for juvenile dermatomyositis and other paediatric idiopathic inflammatory myopathies: 10 years experience: the juvenile Dermatomyositis National (UK and Ireland) cohort biomarker study and repository for idiopathic inflammatory myopathies. Rheumatology (Oxford) 2011; 50(1):137–145.
8. Brown VE,Pilkington CA, Feldman BM, Davidson JE; Network for Juvenile Dermatomyositis, Paediatric Rheumatology European Society (PReS). An international consensus survey of the diagnostic criteria for juvenile dermatomyositis (JDM). Rheumatology (Oxford) 2006; 45(8):990-993.
9. Pachman LM, Abbott K, Sinacore JM, et al. Duration of illness is an important variable for untreated children with juvenile dermatomyositis. J Pediatr 2006; 148(2):247-253.
How to Cite
Aliu, R., Aliyu, L. I., Obiagwu, P. N., Olatoke, L., & Ebisike, J. K. (2020). Juvenile dermatomyositis in a 14-year old Nigerian girl. Archive of Clinical Cases, 7(1), Arch Clin Cases 2020; 7(1):5-9. https://doi.org/10.22551/2020.26.0701.10165
Section
Case Reports

How to Cite

Aliu, R., Aliyu, L. I., Obiagwu, P. N., Olatoke, L., & Ebisike, J. K. (2020). Juvenile dermatomyositis in a 14-year old Nigerian girl. Archive of Clinical Cases, 7(1), Arch Clin Cases 2020; 7(1):5-9. https://doi.org/10.22551/2020.26.0701.10165