Pediatric pancreatic Burkitt lymphoma with obstructive jaundice: case report of a six-year-old child

Imane Athmani, Marie-Amelyne Le Rouzic, Julie Valduga, Ludovic Mansuy, Audrey Contet, Marie-Agnès Galloy, Fanny Fouyssac, Pascal Chastagner

Abstract


Introduction: Burkitt lymphoma represents about 50% of non-Hodgkin lymphomas and 3% of cancers in children. It commonly affects the abdomen; however, pancreatitis is a very rare initial presentation. Less than 10 cases with this presentation are reported in the literature. Observation: We report the case of a six-year-old girl who presented a rapidly progressing obstructive jaundice evolving for a week. The LDH rate was not increased. Medical imaging has shown a global increase in the size of the pancreas, homogeneous hepatomegaly with dilatation of the gallbladder and the intra-hepatic bile ducts, and infiltration of the left ovary, without ascites. The patient was diagnosed with pancreatic Burkitt Lymphoma after an endoscopic exploration and tumor biopsy. Conclusion: While extremely rare, Burkitt lymphoma should be evoked in the case of pancreatitis with a global increase of the pancreas size, associated with other intra-abdominal organ infiltration in the pediatric population.

Keywords


Burkitt lymphoma; pancreatic tumor; obstructive jaundice; children; chemotherapy

Full Text:

PDF

References


Grajo JR, Mark L. Kayton ML, Steffensen TS, et al. Presentation of ileal Burkitt lymphoma in Children. J Radiol Case Rep 2012; 6:27–38.

Kassira N, Pedroso FE, Cheung MC, et al. Primary gastrointestinal tract lymphoma in the pediatric patient: review of 265 patients from the SEER registry. J Pediatr Surg 2011; 46:1956-1964.

Francis IR, Glazer GM. Burkitt’s lymphoma of the pancreas presenting as acute pancreatitis. J Comput Assist Tomogr 1982; 6:395-397.

Merkle EM, Bender G, Brambs HJ. Imaging finding in pancreatic lymphoma: differential aspects. Am J Roentgenol 2000; 174:671-675.

Koca T, Aslan N, Dereci S, et al. Burkitt lymphoma with unusual presentation: Acute pancreatitis. Pediatr Int 2015; 57:775-777.

Wang YJ, Jeng CM, Wang YC, et al. Primary pancreatic Burkitt’s lymphoma mimicking carcinoma with obstructive jaundice and very high CA19-9. Eur J Gastroenterol Hepatol 2006; 18:537-540.

Mahajan V, Qian YW, Blake B, et al. Sporadic Burkitt lymphoma presenting as acute pancreatitis, concurrent sinusitis, and enlarged adenoids. Case Reports in Pediatrics 2016; 2016:3862175. doi: 10.1155/2016/3862175.

Akil M, Kaya A, Selcuk Bektas M, et al. Burkitt’s lymphoma causing acute pancreatitis in a child. J Acute Dis 2013; 2:159-160.

Aftandilian CC, Friedmann AM. Burkitt lymphoma with pancreatic involvement. J Pediatr Hematol Oncol 2010; 32:338-340.

Amodio J, Brodsky JE. Pediatric Burkitt lymphoma presenting as acute pancreatitis: MRI characteristics. Pediatr Radiol 2010; 40:770-772.

Nistala SS, Sawalakhe NR, Thiruvengadam NR, et al. A rare case of primary Burkitt lymphoma in a young indian male. Case report and Review of the Literature. J Pancreas 2009; 10: 686-689.

Novoselac VA, Katz RJ, Lessen DS, et al. Burkitt’s lymphoma arising in the pancreas. J Clin Oncol 2005 ; 23(16 Suppl):6740.

Saglam M, Yilmaz M, Refik MM, et al. A case of pancreatic Burkitt lymphoma: radiological findings. Diagn Interv Radiol 2009, 15:39-42.




DOI: http://dx.doi.org/10.22551/2017.17.0404.10114

Copyright (c) 2017 Imane Athmani, Marie-Amelyne Le Rouzic, Julie Valduga, Ludovic Mansuy, Audrey Contet, Marie-Agnès Galloy, Fanny Fouyssac, Pascal Chastagner

Creative Commons License
Archive of Clinical Cases is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

 

ISSN: 2360-6975