Male breast cancer: quite rare, quite advanced, quite challenging

Iulian Radu, Andrian Panuța, Mihaela Buna-Arvinte, Cristina Terinte, Dan Ferariu, Dragos Viorel Scripcariu, Viorel Scripcariu

Abstract


Male breast cancer (MBC) is a rare disease with peculiarities that differentiate it from female breast cancer. We present the experience of our surgical oncology unit in the management of MBC. Over a period of 4 years and 6 months 10 cases of MBC were diagnosed by physical examination, imaging (ultrasound and/or mammography) and tumor biopsy (core biopsy, fine needle aspiration or extemporaneous histologic exam), underwent surgery (mainly modified Madden radical mastectomy) performed by a single surgical team and were managed by a single oncology committee. The results of our retrospective study are similar with data revealed in literature. Two of our MBC cases were of rare histological type and uncommon presentation, namely synchronous bilateral invasive cribriform carcinoma and adenomyoepithelioma of the male breast.

Keywords


male breast cancer, invasive cribriform carcinoma of male breast, morbidity

Full Text:

PDF

References


Groheux D, Hindié E, Marty M, et al. 18F-FDG-PET/CT in staging, restaging, and treatment response assessment of male breast cancer. Eur J Radiol 2014; 83(10):1925-1933.

Yu XF, Yang HJ, Yu Y, Zou DH, Miao LL. A prognostic analysis of male breast cancer (MBC) compared with post meno¬pausal female breast cancer (FBC). PLoS One 2015; 10(8):e0136670.

Sousa B, Moser E, Cardoso F. An update on male breast cancer and future directions for research and treatment. Eur J Pharmacol 2013; 717(1-3):71-83.

Fentiman IS, Fourquet A, Hortobagyi GN. Male breast cancer. Lancet 2006; 367(9510):595-604.

Sasco AJ, Lowenfels AB, Pasker-de Jong P. Review article: epidemiology of male breast cancer. A meta‐analysis of published case‐control studies and discussion of selected aetiological factors. Int J Cancer 1993; 53(4):538-549.

Cardoso F, Bartlett J, Slaets L, et al. Abstract S6-05: Characterization of male breast cancer: First results of the EORTC10085/TBCRC/ BIG/NABCG international male BC program. Cancer Res 2015; 75:S6-05.

Johansson I, Killander F, Linderholm B, Hedenfalk I. Molecular profiling of male breast cancer – lost in translation? Int J Biochem Cell Biol 2014; 53:526-535.Kahla PB, Cassaro S, Vladimir FG, Wayne MG, Cammarata A. Bilateral synchronous breast cancer in a male. Mt Sinai J Med 2005; 72(2):120-123.

Nishimura R, Ohsumi S, Teramoto N, Yamakawa T, Saeki T, Takashima S. Invasive cribriform carcinoma with extensive microcalcifications in the male breast. Breast Cancer 2005; 12(2):145-148.

Acevedo C, Amaya C, López-Guerra JL. Rare breast tumors: review of the literature. Rep Pract Oncol Radiother 2013; 19(4):267-274.

Farrokh F, Ansaripour E, Rastegar YF. Simultaneous bilateral male breast cancer: A case report and review of the literature. Iranian J Cancer Prev 2010; 3(4):199-203.




DOI: http://dx.doi.org/10.22551/2017.14.0401.10086

Copyright (c) 2017 Iulian Radu, Andrian Panuța, Mihaela Buna-Arvinte, Cristina Terinte, Dan Ferariu, Dragos Viorel Scripcariu, Viorel Scripcariu

Creative Commons License
Archive of Clinical Cases is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

 

ISSN: 2360-6975