Porokeratosis – report of two cases
Abstract
The term of porokeratosis refers to a group of specific disorders of keratinization clinically characterized by atrophic patches surrounded by an elevated hyperkeratotic border and histologically by the cornoid lamella. Multiple clinical variants of porokeratosis are recognized. Herein we report two cases of porokeratosis, one case of disseminated superficial actinic porokeratosis and the other one of atypical porokeratosis of Mibelli. Mibelli typically has an early onset and the lesions are large and isolated. In both cases, the diagnosis was confirmed by dermatoscopy and skin biopsy. The management of porokeratosis includes many options. In both cases, sun protection, emollients and keratolytics were prescribed with significant improvement.
##plugins.themes.bootstrap3.article.details##
porokeratosis, disseminated superficial actinic porokeratosis, classic porokeratosis of Mibelli, atypical Mibelli form, cornoid lamella
2. Pătraşcu V. Boli dermatologice si infectii sexual-transmisibile. 3rd Edition. Craiova: Sitech, 2014.
3. Kanitakis J, Euvrard S, Faure M, Claudy A. Porokeratosis and immunosuppression. Eur J Dermatol. 1998; 8(7):459-466.
4. Sertznig P, von Felbert V, Megahed M. Porokeratosis: present concepts. J Eur Acad Dermatol Venereol. 2012; 26(4):404-412.
5. Murase J, Gilliam AC. Disseminated superficial actinic porokeratosis co-existing with linear and verrucous porokeratosis in an elderly woman: Update on the genetics and clinical expression of porokeratosis. J Am Acad Dermatol 2010; 63(5):886-891.
6. Koley S, Sarkar J, Choudhary S, Dhara S, Choudhury M, Bhattacharya S. Different morphological variants of hypertrophic porokeratosis and disseminated lesions of porokeratosis of Mibelli: a rare co-existence. Indian J Dermatol Venereol Leprol 2011; 77(2):199-202.
7. Wallner JS, Fitzpatrick JE, Brice SL. Verrucous porokeratosis of Mibelli on the buttocks mimicking psoriasis. Cutis 2003; 72:391–393.
8. Brenemann DL, Brenemann JC. Cutaneous T-cell lymphoma mimicking porokeratosis of Mibelli. J Am Acad Dermatol 1993; 29:1046-1458.
9. Kempf W, Hantschke M, Kutzner H, Burgdorf WHC. Dermatopathology. Springer, 2007.
10. Hayes J, Koo J. Depression and Acitretin: A True Association or a Class Labeling. JDD 2011; 10(4):409-412.
11. Lebwohl MG, Heymann WR, Berth-Jones J, Coulson I. Treatment of Skin Disease- comprehensive therapeutic strategies. 4th Edition. Elsevier Saunders, 2014.
12. Requena L, Requena C, Cockerell CJ. Benign Epidermal Tumors and Proliferations. In: Bolognia J, Jorizzo J, Schaffe J (Ed.) Dermatology. Volume 2. 3rd Edition. Philadelphia: Elsevier Saunders; 2012:1801–1803.
Archive of Clinical Cases is protected by copyright and may be used in accordance with copyright and other applicable laws. Content available at www.clinicalcases.eu and our digital applications is intended for personal noncommercial use.
Authors who submit a manuscript for publication in Archive of Clinical Cases agree to the following terms: a. Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal. b. Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal. c. Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) only after the final version of the manuscript was accepted and published, as it can lead to productive exchanges, as well as earlier and greater citation of published work (See The Effect of Open Access). d. It is compulsory that before submission authors ensure that their work was not published in any other medical journals or pending acceptance for publication and that "Archives of Clinical Cases" is the only beneficiary at that moment if their work/case will be accepted by us.
Guidelines for linking to www.clinicalcases.eu a. The main purpose of the site linking to the Archive of Clinical Casess site should be educational. b. Links should be made to the Archive of Clinical Casess home page (www.clinicalcases.eu) or to the articles abstract. c. It is forbidden to use the Archive of Clinical Casess cover by outside organizations unless permission has been granted in advance, notifying our Secretary. d. Material owned by the Archive of Clinical Cases (including the name, logo, cover, and text) may not be used in any manner that may induce the idea or suggest that the Archive of Clinical Cases is in some way recommending a specific company, product or service. e. You must not use or allow others to access or use, all or any part of our Site or the contents and/or applications on it for commercial purposes without our permission. To seek permission to do anything prohibited by or not contained in these TERMS, or which requires our prior consent or agreement, you can contact us.